Police were called to a home in Annerley, just south of Brisbane’s CBD just before midnight on Tuesday.
Police found the man, 24, with life-threatening injures on a footpath at Junction Terrace in Annerley.
Paramedics tried to revive the man, but he was unable to be saved and died at the scene.
He is believed to have been stabbed in the chest with a large kitchen knife, according to The Courier Mail.
Police have now charged a woman, 24, with the murdering following the death of the young man.
A neighbour who lives directly opposite the home told The Courier Mail a woman pictured in media reports assisting police was not known to them.
“We saw the woman in the blue (forensic evidence) suit on TV being taken for questioning, but we’ve never seen her on the street before,” Tee Phillip said.
“It’s actually the second time police have come to this street today because we had someone try to break into our house earlier today.”
Police Inspector Daniel Bragg told 9 News this morning the man “had a significant stab wound to his chest. Police immediately commenced CPR and continued to perform CPR until the ambulance arrived.”
Emergency crews worked on the man for about 30 minutes.
“There was a female at the scene who is currently assisting police with their inquiries,” Insp Bragg said earlier today.
The woman was earlier taken into custody, and she was assisting police. Police have now announced that the woman, 24, has been charged with murder.
“A crime scene was declared, and specialist officers are working at the site throughout the day,” Queensland Police said in a statement.
Junction Road has been closed between Ipswich Road and King Street. Motorists are advised to avoid to area.
Investigators are appealing for anyone who saw a man and woman walking together, or separately, along Junction Terrace and Ipswich Road between 6pm and midnight last night to contact police.
Anyone in the area with CCTV or dashcam is also urged to come forward.
— with AAP